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1.
Chinese Journal of Zoonoses ; 36(5):403-409, 2020.
Article in Chinese | GIM | ID: covidwho-1726193

ABSTRACT

Since the outbreak of SARS, coronavirus has caused yet another epidemic in China for the second time in 2020. When comparing these two epidemics, lots of similarities were found in such as "when" and "where". This article analyses the SARS epidemic and related studies on its natural host, comparing with newest discoveries of the new coronavirus, thus providing a reference view of the current epidemic and scientific reference for disease control.

2.
Curr Pharm Biotechnol ; 23(6): 818-827, 2022.
Article in English | MEDLINE | ID: covidwho-1305597

ABSTRACT

In order to curve the ongoing trend of the COVID-19 pandemic and save more lives, effective treatments against COVID-19 are urgently needed. Compared to developing new drugs, which may take too much time, it's more efficient and cost-effective to repurpose existing drugs in the treatment of COVID-19. Fortunately, some of the shared features of COVID-19 and other wellknown diseases make it possible to use old strategies to combat this new challenge. In this paper, we reviewed various possible strategies of drug repurposing in the treatment of COVID-19 and explored the possible scientific mechanisms behind each strategy.


Subject(s)
COVID-19 Drug Treatment , Drug Repositioning , Antiviral Agents/therapeutic use , Humans , Pandemics , SARS-CoV-2
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